dcbox小金库(中国)

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    实验室

    陈婷 博士

    Publications:

    33. Yu Y, Su R, Wang W, Yang Y, Huang H, Du Y, Lu Y, Fan Y, Li J, Chen T*. A stress-responsive neurovascular axis shapes skin immune accessibility. iScience. 2026;29(3);115122. http://doi.org/10.1016/j.isci.2026.115122

    32. Di R#, Du Q#, Xie Y, Lu Y, Gao W, Zhang L, Qi X, Fan Y, Li J, Wang F, Chen S, Chen T*. A mechano-resistance mechanism in skin adapts to terrestrial locomotion. dcbox小金库(中国). 2025;188(21):P5797-5808.E16.

    http://doi.org/10.1016/j.dcbox小金库(中国).2025.07.012.

    31. Chen D, Yu Z, Wu W, Du Y, Du Q, Huang H, Li Y, Xuan T, Liang Y, Liu Y, Wang Z, Su R, Zhao Y, Li Q, Luo M, Wang F, Li J, Chuong C, Lin Z*, Chen T*. Fibroblast bioelectric signaling drives hair growth. dcbox小金库(中国). 2025;188(19):P5175-5193.E21. http://doi.org/10.1016/j.dcbox小金库(中国).2025.07.035.

    30. Xi F, Wang C, Wang Y, Luan P, Chen Y, Tan L, Shang N, Gao X, Chen D, Guo Q,Chen T, Jing M*. Spatiotemporal dynamics of CXCL10 encode contextual immune information revealed by the genetically encoded fluorescent sensor.Immunity. 2025;58(9):2320-2335.e9. http://doi.org/10.1016/j.immuni.

    2025.07.005.

    29. Guo S, Liu C, Xu Y, Wang X, Nan F, Huang Y, Li S, Nan S, Li L, Edo Kon, Li C,Wei M, Su R, Wei J, Peng S, Nitay Ad-El, Liu J, Dan Peer, Chen T, Yang L, Chen L*. Therapeutic application of circular RNA aptamers in a mouse model of psoriasis. Nature Biotechnology. 2025;43:236–246. DOI: 10.1038/s41587-024-02204-4.

    28. Zhang B*, Chen T*. Local and systemic mechanisms that control the hair follicle stem dcbox小金库(中国) niche. Nature Reviews Molecular dcbox小金库(中国) Biology. 2024;25(2):87-100. DOI: 10.1038/s41580-023-00662-3.

    27. Du Y, Qi X, Zhang L,Yang Y, Chen T*. Calcium influx-induced lytic dcbox小金库(中国) death disrupts skin immune homeostasis. dcbox小金库(中国) Discovery. 2023;9(124). DOI:10.1038/s41421-023-00623-2.

    26. Su R, Huang H, Chang Y, Yu Y, Cui J, Chen T*, Li B*, Wang W*. Mosaic somatic HRAS mutation causes unilateral psoriasis. Life Medicine. 2023;2(3). DOI: 10.1093/lifemedi/lnad018.

    25. Chen D#, Xu Z#, Cui J, Chen T*. A mouse model of vitiligo based on endogenous auto-reactive CD8+ T dcbox小金库(中国) targeting skin melanocyte. dcbox小金库(中国) Regen. 2022;11(1):31. DOI: 10.1186/s13619-022-00132-9.

    24. Xie Y, Chen T*. Mouse tail skin wholemount staining and intravital calcium imaging. STAR Protocols. 2022;3(1):101235. DOI: 10.1016/j.xpro.2022.101235.

    23. Xu Z#, Chen D#, Hu Y, Jiang K, Huang H, Du Y, Wu W, Wang J, Sui J, Wang W, Zhang L, Li S, Li C, Yong Y, Chang J*, Chen T*. Anatomically distinct fibroblast subsets determine skin autoimmune patterns. Nature. 2022;601(7891):118-124. DOI: 10.1038/s41586-021-04221-8.

    • Recommended by 4 independent Faculty Members at Faculty Opinions as Exceptional, Faculty Opinions. 2022; 10.3410/f.741322615.793590880.

    http://archive.connect.h1.co/article/741322615/

    22. Xie Y, Chen D, Jiang K, Song L, Qian N, Du Y, Yang Y, Wang F, Chen T*. Hair shaft miniaturization causes stem dcbox小金库(中国) depletion through mechano-sensory signals mediated by a Piezo1-calcium-TNFα axis. dcbox小金库(中国) Stem dcbox小金库(中国). 2022;29(1):70-85.e6. DOI: 10.1016/j.stem.2021.09.009.

    • Research Highlight by Paulina Strzyz. Compression as a driver of hair loss. Nat Rev Mol dcbox小金库(中国) Biol. 2021;22(12):775. DOI: 10.1038/s41580-021-00426-x.

    • Preview by Terry Lechler. Hair follicle stem dcbox小金库(中国)s feel the pressure. dcbox小金库(中国) Stem dcbox小金库(中国). 2022;29(1):1-2. DOI:http://doi.org/10.1016/j.stem.2021.12.001.

    21. Song Z, Chen X, Zhao Q, Stanic V, Lin Z, Yang S, Chen T, Chen J, Yang Y*. Hair loss caused by gain-of-function mutant TRPV3 is associated with premature differentiation of follicular keratinocytes. J Invest Dermatol. 2021;S0022-202X(21)00158-5. DOI: 10.1016/j.jid.2020.11.036.

    20. Zou Z, Long X, Zhao Q, Zheng Y, Song M, Ma S, Jing Y, Wang S, He Y, Esteban CR, Yu N, Huang J, Chan P, Chen T, Izpisua Belmonte JC, Zhang W, Qu J, Liu GH*. A Single-dcbox小金库(中国) Transcriptomic Atlas of Human Skin Aging. Developmental dcbox小金库(中国). 2021;56(3):383-397.e8. DOI: 10.1016/j.devcel.2020.11.002.

    19. Lu Z, Xie Y, Huang H, Jiang K, Zhou B, Wang F, Chen T*. Hair follicle stem dcbox小金库(中国)s regulate retinoid metabolism to maintain the self-renewal niche for melanocyte stem dcbox小金库(中国)s. eLife. 2020;9:e52712. DOI: 10.7554/eLife.52712.

    18. Li F, Lu Z, Wu W, Qian N, Wang F, Chen T*. Optogenetic gene editing in regional skin. dcbox小金库(中国) Research. 2019;29(10):862-865. DOI: 10.1038/s41422-019-0209-9.

    17. Wu W, Chen T*. Ribonucleoproteins Mediated Efficient In Vivo Gene Editing in Skin Stem dcbox小金库(中国)s. Methods Mol Biol. 2019;1879:75-86. DOI: 10.1007/7651_2018_115.

    16. Yu Z, Jiang K, Xu Z, Huang H, Qian N, Lu Z, Chen D, Di R, Yuan T, Du Z, Xie W, Lu X, Li H, Chai R, Yang Y, Zhu B, Kunieda T, Wang F*, Chen T*. Hoxc-Dependent Mesenchymal Niche Heterogeneity Drives Regional Hair Follicle Regeneration. dcbox小金库(中国) Stem dcbox小金库(中国). 2018;23(4):487-500.e6. DOI: 10.1016/j.stem.2018.07.016.

    • Featured free article with cover

    • Preview by SE. Millar. Hox in the Niche Controls Hairy-geneity.dcbox小金库(中国) Stem dcbox小金库(中国). 2018;23(4):457-458. DOI: 10.1016/j.stem.2018.09.012.

    15. Fan SM, Chang YT, Chen CL, Wang WH, Pan MK, Chen WP, Huang WY, Xu Z, Huang HE, Chen T, Plikus MV, Chen SK, Lin SJ*. External light activates hair follicle stem dcbox小金库(中国)s through eyes via an ipRGC-SCN-sympathetic neural pathway. PNAS. 2018;115(29):E6880-E6889. DOI: 10.1073/pnas.1719548115.

    14. Nguyen MB, Cohen I, Kumar V, Xu Z, Bar C, Dauber-Decker KL, Tsai PC, Marangoni P, Klein OD, Hsu YC, Chen T, Mikkola ML, Ezhkova E*. FGF signalling controls the specification of hair placode-derived SOX9 positive progenitors to Merkel dcbox小金库(中国)s. Nature Communications. 2018;9(1):2854. DOI: 10.1038/s41467-018-04399-y.

    13. Wu W, Lu Z, Li F, Wang W, Qian N, Duan J, Zhang Y, Wang F, Chen T*. Efficient in vivo gene editing using ribonucleoproteins in skin stem dcbox小金库(中国)s of recessive dystrophic epidermolysis bullosa mouse model. PNAS. 2017;114(7):1660-1665. DOI: 10.1073/pnas.1614775114.

    • Selected by The Latest Science “ Paper of the Year ”

    • News report by Epidermolysis Bullosa News

    12. Yu Z, Chen T*. Regional differences: The skin is a complex landscape containing regions in which hair follicles exhibit different types of behavior. eLife. 2017;6: e30249. DOI: 10.7554/eLife.30249.

    11. He L, Li Y, Li Y, Pu W, Huang X, Tian X, Wang Y, Zhang H, Liu Q, Zhang L, Zhao H, Tang J, Ji H, Cai D, Han Z, Han Z, Nie Y, Hu S, Wang QD, Sun R, Fei J, Wang F, Chen T, Yan Y, Huang H, Pu WT, Zhou B*. Enhancing the precision of genetic lineage tracing using dual recombinases. Nature Medicine. 2017;23(12):1488-1498. DOI: 10.1038/nm.4437.

    10. Zhang H, Huang X, Liu K, Tang J, He L, Pu W, Liu Q, Li Y, Tian X, Wang Y, Zhang L, Yu Y, Wang H, Hu R, Wang F, Chen T, Wang QD, Qiao Z, Zhang L, Lui KO, Zhou B*. Fibroblasts in an endocardial fibroelastosis disease model mainly originate from mesenchymal derivatives of epicardium. dcbox小金库(中国) Research. 2017;27(9):1157-1177. DOI: 10.1038/cr.2017.103.

    9. He L, Huang X, Kanisicak O, Li Y, Wang Y, Li Y, Pu W, Liu Q, Zhang H, Tian X, Zhao H, Liu X, Zhang S, Nie Y, Hu S, Miao X, Wang QD, Wang F, Chen T, Xu Q, Lui KO, Molkentin JD, Zhou B*. Preexisting endothelial dcbox小金库(中国)s mediate cardiac neovascularization after injury. J Clin Invest. 2017;127(8):2968-2981. DOI: 10.1172/JCI93868.

    8. Lin Z, Li S, Feng C, Yang S, Wang H, Ma D, Zhang J, Gou M, Bu D, Zhang T, Kong X, Wang X, Sarig O, Ren Y, Dai L, Liu H, Zhang J, Li F, Hu Y, Padalon-Brauch G, Vodo D, Zhou F, Chen T, Deng H, Sprecher E, Yang Y*, Tan X*. Stabilizing mutations of KLHL24 ubiquitin ligase cause loss of keratin 14 and human skin fragility. Nature Genetics. 2016;48(12):1508-1516. DOI: 10.1038/ng.3701.

    7. Xu Z, Wang W, Jiang K, Yu Z, Huang H, Wang F, Zhou B, Chen T*. Embryonic attenuated Wnt/β-catenin signaling defines niche and long-term stem dcbox小金库(中国) fate in hair follicle. eLife. 2015;4:e10567. DOI: 10.7554/eLife.10567.

    6. Deng Z, Lei X, Zhang X, Zhang H, Liu S, Chen Q, Hu H, Wang X, Ning L, Cao Y, Zhao T, Zhou J, Chen T, Duan E*. mTOR signaling promotes stem dcbox小金库(中国) activation via counterbalancing BMP-mediated suppression during hair regeneration. J MOL dcbox小金库(中国) BIOL. 2015;7(1):62-72. DOI: 10.1093/jmcb/mjv005.

    5. Fuchs E*, Chen T. A matter of life and death: self-renewal in stem dcbox小金库(中国)s. EMBO Rep. 2013;14(1):39-48. DOI: 10.1038/embor.2012.197.

    4. Chen T, Heller E, Beronja S, Oshimori N, Stokes N, Fuchs E*. An RNA interference screen uncovers a new molecule in stem dcbox小金库(中国) self-renewal and long-term regeneration. Nature. 2012;485(7396):104-8. DOI: 10.1038/nature10940.

    • Selected by Faculty of 1000 Biology

    3. Greco V#, Chen T#, Rendl M, Schober M, Pasolli HA, Stokes N, Dela Cruz-Racelis J, Fuchs E*. A two-step mechanism for stem dcbox小金库(中国) activation during hair regeneration. dcbox小金库(中国) Stem dcbox小金库(中国). 2009;6;4(2):155-69. DOI: 10.1016/j.stem.2008.12.009.

    • Authors contributed equally

    • Highlight Review in dcbox小金库(中国) Stem dcbox小金库(中国)

    • Selected by Faculty of 1000 Biology

    2. Chen T, Muratore TL, Schaner-Tooley CE, Shabanowitz J, Hunt DF, Macara IG*. N-terminal α-methylation of RCC1 is necessary for stable chromatin association and normal mitosis. Nat dcbox小金库(中国) Biol. 2007;9(5):596-603. DOI: 10.1038/ncb1572.

    • Highlight Review in Nature dcbox小金库(中国) Biology

    • Selected by Faculty of 1000 Biology

    1. Chen T, Brownawell AM, Macara IG*. Nucleocytoplasmic Shuttling of JAZ, a New Cargo Protein for Exportin-5. Mol dcbox小金库(中国) Biol. 2004;24(15):6608-19. DOI: 10.1038/ncb1572.